The purpose of the current study was to examine the relationship among work-family conflict (WFC) /facilitation (WFF),job demands,job resources,psychological stress response,and work engagement from the view of the Job Demands-Resources model. Data was collected using a mailing method of 240 employees working in 10 different social welfare facilities. Results showed that job demands,specifically emotional burden,enhanced WFC,which in turn led to high psychological stress response. Job resources,specifically support from family and friends,impacted WFF,which in turn led to high work engagement. In addition,Family to work conflict (Fwc) moderated the relationship between work to family facilitation (Wff) and work engagement. We discussed that welfare facilities should try to reduce WFC and improve WFF,such as family-friendly workplace policies,to promote the mental health of care staff.